How strong are Diazepam 2 mg tablets

Diazepam-ratiopharm 2 mg tablets

Diazepam-ratiopharm® 2 mg must not be taken

  • if you are allergic to diazepam, other benzodiazepines or any of the other ingredients of this medicine (listed in section 6)
  • if you have ever been dependent on alcohol, drugs or medicines
  • in the case of acute poisoning with alcohol, sleeping pills and painkillers or with drugs for the treatment of mental and emotional disorders (neuroleptics, antidepressants, lithium preparations)
  • for severe, pathological muscle weakness (myasthenia gravis)
  • if breathing is severely impaired
  • if you stop breathing for a short time during sleep (sleep apnea syndrome)
  • with severe liver damage, e.g. B. jaundice with biliary obstruction (cholestatic jaundice)
  • in newborns and infants under 6 months of age
Warnings and Precautions

Talk to your doctor or pharmacist before taking Diazepam-ratiopharm® 2 mg

  • in disorders of the orderly interaction of muscle groups (spinal and cerebellar ataxias)
  • if you have organ changes in the brain
  • for circulatory and respiratory problems
  • with impaired liver and kidney function
Checks of the blood count and liver function are recommended for long-term use.

Because of the pronounced muscle slackening effect of Diazepam-ratiopharm® 2 mg, caution is advised, especially in older patients (risk of falling!).

Diazepam-ratiopharm® 2 mg should not be taken at the same time as alcohol and / or drugs with a depressant effect on the central nervous system. Concomitant use can increase the effect of Diazepam-ratiopharm® 2 mg and possibly lead to unconsciousness and a flattening of the cardiovascular function and / or breathing, which require emergency treatment.

Tolerance development

Repeated use of Diazepam-ratiopharm® 2 mg for a few weeks may lead to a loss of effectiveness (due to the development of tolerance to the sedative).

Dependency development

As with other sedatives, taking Diazepam-ratiopharm® 2 mg can lead to the development of physical and emotional dependence. The risk of dependence increases with dose and duration of treatment, but it already exists with the prescribed dose and shorter treatment.

If you are currently dependent on drugs with a depressant effect on the central nervous system or on alcohol, you should, except in the case of acute withdrawal reactions,

Do not take Diazepam-ratiopharm® 2 mg.

Uninterrupted use for more than 4 weeks should be avoided as it can lead to dependence.

Discontinuation of therapy / withdrawal symptoms

If physical addiction has developed, withdrawal symptoms will occur if treatment is stopped suddenly. These can manifest themselves in headaches, muscle pain, states of fear or tension, inner restlessness, sweating, tremors, sleep disorders, increased dreaming, mood changes, confusion and irritability.

In severe cases, the following symptoms may also occur: impaired perception of oneself or the environment (depersonalization, derealization), hypersensitivity to light, noise and physical contact, numbness and tingling sensation in the arms and legs, hallucinations or epileptic seizures.

Even when a shorter treatment with Diazepam-ratiopharm® 2 mg is ended, sudden discontinuation may temporarily increase anxiety, tension and excitement

occur. Mood changes, sleep disorders and restlessness are possible side effects. It is therefore recommended to stop treatment by gradually reducing the dose.

Memory problems

Diazepam-ratiopharm® 2 mg can cause temporary memory lapses (anterograde amnesia). This means that you are e.g. B. can no longer remember actions that you performed after taking Diazepam-ratiopharm® 2 mg. This risk increases with the dose level and can be reduced by a sufficiently long uninterrupted sleep period (7-8 hours).

Psychological and “paradoxical” reactions

When using Diazepam-ratiopharm® 2 mg, especially in older patients or children, hallucinations and a reversal of effects (so-called "paradoxical reactions" such as restlessness, irritability, aggressive behavior, nightmares, hallucinations, delusions, inappropriate behavior and others) can occur Behavior disorders) (see 4. "What side effects are possible?"). In such cases, treatment with Diazepam ratiopharm® 2 mg should be stopped.

Psychoses

Diazepam-ratiopharm® 2 mg is not recommended for the initial treatment of mental and emotional disorders (psychoses).

depressions

Diazepam-ratiopharm® 2 mg should not be used on its own for the treatment of depression or anxiety that occurs with depression. Under certain circumstances, the clinical picture of depression can be exacerbated if the underlying disease is not adequately treated with appropriate drugs (antidepressants) (risk of suicide).

Children and adolescents

Diazepam-ratiopharm® 2 mg must not be used in newborns and infants up to the age of 6 months (see under “Diazepam-ratiopharm® 2 mg must not be taken”).

Children and adolescents should only be treated with Diazepam-ratiopharm® 2 mg if there are compelling reasons.

Elderly and debilitated patients

A lower dose is recommended in elderly or debilitated patients. In elderly patients, caution is advised because of the risk of falling, especially when getting up at night (see 3. under "Special patient groups").

Patients with impaired liver or kidney function

Caution should be exercised in patients with impaired liver or kidney function. Your doctor will adjust your dosage (see 3. under "Special patient groups").

Diazepam-ratiopharm® 2 mg must not be used by patients with severe liver damage (see under “Diazepam-ratiopharm® 2 mg must not be taken”).

Taking Diazepam-ratiopharm® 2 mg together with other medicaments

Tell your doctor or pharmacist if you are taking / using, have recently taken / used or may take / use any other medicines

When used with the following drugs, there may be a mutual reinforcement of the effect and possibly an increase in side effects:

- Sleeping pills, sedatives, painkillers and anesthetics

  • Medicines for the treatment of mental and emotional diseases (neuroleptics, antidepressants, lithium preparations)
  • Medicines used to treat epileptic seizures
  • anti-anxiety drugs (anxiolytics)
  • certain medicines for allergies (sedating antihistamines)
  • Medicines used to treat certain types of narcolepsy (sodium oxybate)
  • certain medicines used to treat HIV (HIV protease inhibitors)
When used with the following drugs, the effect of Diazepam-ratiopharm® 2 mg can be prolonged and intensified:
  • Cimetidine or omeprazole (medicines used to treat stomach ulcers, for example)
  • Disulfiram (medicine used to treat alcohol withdrawal)
  • Ketoconazole (medicine to treat fungal infections)
  • Fluvoxamine and fluoxetine (medicines used to treat depression)
Diazepam-ratiopharm® 2 mg can increase the effects and possibly the side effects of the following medicines:
  • Opiate-type painkillers (the mood-enhancing effect may be amplified and thus the development of dependency accelerated)
  • Medicines that reduce muscle tension (muscle relaxants) (there may be an increased risk of falls, especially in elderly patients and with higher doses)
Theophylline (medicine used to treat e.g. asthma)

In low doses, theophylline cancels the sedation caused by Diazepam-ratiopharm® 2 mg.

Levodopa (drug used to treat Parkinson's disease)

Diazepam-ratiopharm® 2 mg can inhibit the effect of levodopa.

Phenytoin and phenobarbital (medicines used to treat epileptic seizures)

In rare cases, Diazepam-ratiopharm® 2 mg can inhibit the breakdown of phenytoin in the body and increase its effect. Phenobarbital and phenytoin can help break down

Accelerate Diazepam-ratiopharm® 2 mg.

Other medicines

In patients who are on long-term treatment with other drugs, such as B. certain drugs against high blood pressure (centrally acting antihypertensive drugs, beta-receptor blockers), anti-coagulant drugs and drugs to strengthen the heart (anticoagulants, cardiac glycosides), the type and extent of interactions cannot be foreseen. Therefore, special caution is required when taking the preparation at the same time, especially at the beginning of treatment. Tell your doctor if you are receiving such long-term treatment.

Diazepam excretion can be accelerated in smokers.

Due to the slow elimination of diazepam from the body, you must still expect possible interactions even after you have stopped treatment with Diazepam-ratiopharm® 2 mg.

Taking Diazepam-ratiopharm® 2 mg together with alcohol

Avoid the consumption of alcohol during treatment with Diazepam-ratiopharm® 2 mg, as alcohol changes and intensifies the effect of Diazepam-ratiopharm® 2 mg in an unforeseeable way.

pregnancy and breast feeding period

Ask your doctor for advice before taking this medicine if you are pregnant or breastfeeding, if you suspect you may be pregnant or planning to become pregnant.

During pregnancy you should only use Diazepam-ratiopharm® 2 mg in exceptional cases for compelling reasons. If you become pregnant or suspect that you are pregnant during treatment with Diazepam-ratiopharm®, please inform your doctor immediately.

Long-term use of Diazepam-ratiopharm® 2 mg during pregnancy can lead to withdrawal symptoms in the newborn. The administration of larger doses before or during childbirth can cause the infant to have low body temperature, low blood pressure, decreased breathing, decreased muscle tension and poor drinking (so-called "floppy infant syndrome").

You should not use Diazepam-ratiopharm® 2 mg if you are breast-feeding, as Diazepam, the active substance in Diazepam-ratiopharm® 2 mg, and its breakdown products are excreted in breast milk. If treatment is unavoidable, breastfeeding should be stopped.

Driving and using machines

Even when used as directed, this medicinal product can change the ability to react to such an extent that the ability to actively drive or operate machines is impaired. This applies even more in combination with alcohol.

You should therefore refrain from driving vehicles, operating machines or other dangerous activities entirely, at least during the first few days of treatment. The decision in each individual case is made by the attending physician, taking into account the individual reaction and the respective dosage.

Diazepam-ratiopharm® 2 mg contains lactose

Therefore, please only take Diazepam-ratiopharm® 2 mg after consulting your doctor if you know that you suffer from an intolerance to certain sugars.