Is there a Pac woman

Cranberry: Are Products Used To Prevent Cystitis?

What should be considered when using cranberry products?

Cranberry food supplements do not require an "instruction leaflet" to provide information about contraindications, adverse effects or drug interactions. However, it is known in specialist circles that incorrectly used plant extracts can be harmful to health. Elderly people who have to take medication on a regular basis are particularly at risk. Even with cranberry products, interactions with drugs such as B. anticoagulants known.

Cranberries and juice contain oxalates. A compound that is common in kidney stones. Regular consumption is therefore not recommended for people who are prone to kidney stones.

What are cranberries?

The bright red cranberry (botanical: Vacciunium macrocarpon, also called cranberry or large-fruited cranberry) is native to Northeast America and is grown commercially there on a large scale. It is related to the wild lingonberry in our areas and was already used by the Native Americans in a variety of ways, including medicinally. The flesh is firm, crisp and quite sour. The direct or mother juice has a strong, fruity and sour taste. When dried, the berry tastes better because of the added sugar. Cranberries are now also grown in Germany, e.g. in Lower Saxony.

What ingredients do cranberries contain?

The berries have a high content of phytochemicals such as proanthocyanidins (PAC, also OPC) and antioxidants. PAC should not only be responsible for the antioxidant effect, but also prevent pathogenic bacteria from adhering to the bladder wall. This is supposed to prevent urinary tract infections.

There was initial evidence from research for the statement "can prevent bacteria from adhering to the walls of the urinary tract and bladder". Bacteria such as the intestinal bacterium Escherichia Coli could thus be better flushed out with the urine, which can have a preventive effect against inflammation. The ingredients of the cranberry are said to be responsible for this, especially the PAC. These relationships have only been assumed so far and have not yet been scientifically proven; the possible mechanism of action is also unknown.

The European Commission decided in 2017 that a mechanical mode of action such as the adhesion of bacteria to proanthocyanidins (PAC) is extremely unlikely. The decisive factor is an opinion from the European Medicines Agency (EMA), according to which metabolic products of the PAC and other components of cranberries could have more of a pharmacological effect.

The European Commission has "powder made from cranberry extract" with a Maximum content of a maximum of 350 mg per day Approved as a novel food ingredient in nutritional supplements for adults. However, the ingredient may only be used by Ocean Spray Cranberry Inc., USA. The new ingredient can also be labeled as "powder made from cranberry extract" and may only be produced using a certain process. This approval was given on the basis of scientific knowledge and data that will not be published until 2023. Among other things, it is said to have a high proportion of proanthocyanidins, which lower blood pressure, inhibit the formation of tumors and prevent blood clots from forming.

What does the PAC value say?

The content of proanthocyanidins (PAC) is advertised on many food supplements. The problem is that there is still no generally recognized method for determining the PAC value in cranberry products. In addition, the content in the product says nothing about the bioavailability in the body.

The daily dose is often given as 36 mg PAC. This can be traced back to the French Food Authority (AFSSA). In 2004, AFSSA concluded that a bladder health statement applied to both the cranberry juice and the powder. The minimum amount required was set at 36 mg PAC, which was determined using a specific method. It is now pointed out that the data situation has changed and the preventive effect can no longer be confirmed.